In a city so dismal it's known only as "the Hole," a clan of Sorcerers has been plucking people off the streets to use as guinea pigs for atrocious "experiments" in the black arts. In a dark alley, Nikaido found Caiman, a man with a reptile head and a bad case of amnesia. To undo the spell, they're hunting and killing the Sorcerers in the Hole, hoping that eventually they'll kill the right one. But when En, the head Sorcerer, gets word of a lizard-man slaughtering his people, he sends a crew of "cleaners" into the Hole, igniting a war between two worlds.
Deep in the Hole, the survivors of En's family continue their mission to revive their slain leader with some "enhanced interrogation" of a Cross-Eye member. The rest of the Cross-Eyes finally come face-to-face with their long-lost boss. And Risu, Asu, and an even more powerful Nikaido find themselves on a surprisingly dangerous quest: getting her gyoza business up and running again.