The angel Alexiel loved God, but she rebelled against Heaven when she saw how disgracefully the other angels were behaving. She was finally captured, and as punishment sent to Earth to live an endless series of tragic lives. She now inhabits the body of Setsuna Mudo, a troubled teen in love with his sister Sara. Setsuna's misery mirrors the chaos among the angels, and their combined passions threaten to destroy both Heaven and Earth.
Now that his rivals are out of the way, Angel Rosiel's plans to control Heaven are moving forward, with Lucifer at his side, and Sandalphon under his control. But the Angel of Judgment Uriel is trying to unite the opposition by arranging a meeting between himself and Setsuna on one side, and the Elemental Angels Michael and Raphael on the other. Sandalphon himself has his own ideas and escapes captivity. To fulfill his destiny as destroyer of the world, he needs a physical body, and Sara is the key. Now the race is on to see who will find Sara first: Setsuna and the rebels, or the angel of the apocalypse!