The angel Alexiel loved God, but she rebelled against Heaven when she saw how disgracefully the other angels were behaving. She was finally captured, and as punishment sent to Earth to live an endless series of tragic lives. She now inhabits the body of Setsuna Mudo, a troubled teen in love with his sister Sara. Setsuna's misery mirrors the chaos among the angels, and their combined passions threaten to destroy both Heaven and Earth.
Setsuna and his team have broken into prison to rescue their ally Zaphikel. But they are shocked to find out that they're too late--Zaphikel's wings have already been cut off. Without their protection, he is infected with disease, and is on his way to becoming a flesh-devouring ghoul.
Meanwhile, the evil angel Rosiel chairs a meeting of the leaders of heaven. He announces that he is one step ahead of Setsuna and the rebels, as he knows where they plan to escape to after the prison break. So when Setsuna's team arrives at their destination, they'll find a rather nasty surprise waiting for them!