Inside the O'Briens
From New York Times bestselling author and neuroscientist Lisa Genova comes a “heartbreaking…very human novel” (Matthew Thomas, author of We Are Not Ourselves) that does for Huntington’s disease what her debut novel Still Alice did for Alzheimer’s.
Joe O’Brien is a forty-three-year-old police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, proud father of four children in their twenties, and respected officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to the stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his family’s lives forever: Huntington’s disease.
Huntington’s is a lethal neurodegenerative disease with no treatment and no cure, and each of Joe’s four children has a 50 percent chance of inheriting their father’s disease. While watching her potential future in her father’s escalating symptoms, twenty-one-year-old daughter Katie struggles with the questions this test imposes on her young adult life. As Joe’s symptoms worsen and he’s eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while Katie and her siblings must find the courage to either live a life “at risk” or learn their fate.
Praised for writing that “explores the resilience of the human spirit” (San Francisco Chronicle), Lisa Genova has once again delivered a novel as powerful and unforgettable as the human insights at its core.
Lisa Genova loves listening to audiobooks at night
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As a police officer from an Irish Catholic neighborhood in Boston, Joe O’Brien has always prided himself on his self-control. And with four adult kids still living under his roof, he needs it. There’s JJ, the upstanding fireman hoping to start his own family; Patrick, the rowdy bartender; Meghan, the accomplished but uptight ballet dancer; and Katie, the restless yoga instructor just trying to get them all to take her seriously. Joe loves being their rock, but when he begins to experience bouts of disorganized thinking, temper outbursts, and strange, involuntary movements, his fiercely protective wife, Rosie, drags him to a neurologist. There, they are handed a diagnosis that will change their family forever: Huntington’s disease.
Each of the O’Brien children has a 50 percent chance of inheriting this lethal neurodegenerative disease. A simple blood test can reveal their genetic fate. As Katie observes the devastating symptoms in her once invincible father escala see more