In New Domino City, the hottest game in town is the Turbo Duel, fought from blazingly fast motorcycles called Duel Runners. On the outskirts of New Domino City, in a district known as Satellite, a new Turbo Duel hero emerges—Yusei Fudo! On his custom-built Duel Runner, Yusei takes on all challengers, fighting for his friends and the future of Satellite!
Yusei has defeated the twins Luna and Leo, but they promise him a rematch in Satellite city. On the way to Satellite, Yusei meets Rex Goodwin, who wants Yusei’s help defeating the Skeleton Knight, and although Yusei doesn’t trust this new ally. As the second round of the Grand Prix opens, the sinister Lazar presents the Duelists with a new challenge—face the 12 “Duel Zodiacs” and open the Duel Gate to advance to the final round!